A Concise Synthesis of the Key Tetrahydrofuran Moieties of Caruifolin A and EBC‐342. Issue 44 (5th June 2020)

• Record Type: Journal Article
• Authors: Fernandes, Rodney A.; Bethi, Venkati
• Other Names: Datta Anindya guestEditor.
• Is Part Of: European journal of organic chemistry. Issue 44(2020)
• Page Start: 6922
• Page End: 6928
• Publication Date: 2020-06-05
• Subjects: Allylation -- Germacranolide -- Asymmetric dihydroxylation -- Cyclization -- Natural products; Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1002/ejoc.202000513
• Languages: English
• ISSNs: 1434-193X

Abstract

Abstract : A common strategy for the concise synthesis of the key tetrahydrofuran moieties of caruifolin A and EBC‐342 is presented. Asymmetric dihydroxylation and intramolecular SN 2‐cyclization are key strategic reactions for the synthesis of the furan fragments. Abstract : A common strategy for the synthesis of substituted tetrahydrofuran moieties of caruifolin A and EBC‐342 has been developed based on asymmetric dihydroxylation and intramolecular SN 2‐cyclization.