PrEP Nonadherence, White Coat Dosing, and HIV Risk Among a Cohort of MSM. (7th August 2020)

• Record Type: Journal Article
• Authors: Blair, Cheríe S; Beymer, Matthew R; Kofron, Ryan M; Bolan, Robert K; Jordan, Wilbert C; Haubrich, Richard H; Wohl, Amy R; Landovitz, Raphael J
• Is Part Of: Open forum infectious diseases. Volume 7:Number 8(2020)
• Publication Date: 2020-08-07
• Subjects: MSM -- pre-exposure prophylaxis -- PrEP adherence -- syphilis -- white coat dosing; Communicable diseases -- Periodicals; Medical microbiology -- Periodicals; Infection -- Periodicals; 616.9
• DOI: 10.1093/ofid/ofaa329
• Languages: English
• ISSNs: 2328-8957

Abstract

Abstract: Among a cohort of men who have sex with men in a pre-exposure prophylaxis (PrEP) adherence trial, syphilis requiring treatment was associated with white coat dosing (increased PrEP adherence immediately preceding study visits) when compared with participants with optimal drug concentrations. The findings highlight the need for identifying and reducing barriers to PrEP adherence.