Probabilities of Unranked and Ranked Anomaly Zones under Birth–Death Models. (20th December 2019)

• Record Type: Journal Article
• Authors: Kim, Anastasiia; Rosenberg, Noah A; Degnan, James H
• Editors: Yoder, Anne
• Is Part Of: Molecular biology and evolution. Volume 37:Number 5(2020)
• Page Start: 1480
• Page End: 1494
• Publication Date: 2019-12-20
• Subjects: anomalous gene tree -- coalescent -- gene tree -- phylogeny -- species tree; Molecular biology -- Periodicals; Molecular evolution -- Periodicals; Evolution, Molecular -- Periodicals; Molecular Biology -- Periodicals; 572.8
• DOI: 10.1093/molbev/msz305
• Languages: English
• ISSNs: 0737-4038

Abstract

Abstract: A labeled gene tree topology that is more probable than the labeled gene tree topology matching a species tree is called "anomalous." Species trees that can generate such anomalous gene trees are said to be in the "anomaly zone." Here, probabilities of "unranked" and "ranked" gene tree topologies under the multispecies coalescent are considered. A ranked tree depicts not only the topological relationship among gene lineages, as an unranked tree does, but also the sequence in which the lineages coalesce. In this article, we study how the parameters of a species tree simulated under a constant-rate birth–death process can affect the probability that the species tree lies in the anomaly zone. We find that with more than five taxa, it is possible for species trees to have both anomalous unranked and ranked gene trees. The probability of being in either type of anomaly zone increases with more taxa. The probability of anomalous gene trees also increases with higher speciation rates. We observe that the probabilities of unranked anomaly zones are higher and grow much faster than those of ranked anomaly zones as the speciation rate increases. Our simulation shows that the most probable ranked gene tree is likely to have the same unranked topology as the species tree. We design the software PRANC, which computes probabilities of ranked gene tree topologies given a species tree under the coalescent model.