High Rates of Influenza-Associated Invasive Pulmonary Aspergillosis May Not Be Universal: A Retrospective Cohort Study from Alberta, Canada. (6th January 2020)

• Record Type: Journal Article
• Authors: Schwartz, Ilan S; Friedman, Daniel Z P; Zapernick, Lori; Dingle, Tanis C; Lee, Nelson; Sligl, Wendy; Zelyas, Nathan; Smith, Stephanie W
• Is Part Of: Clinical infectious diseases. Volume 71:Number 7(2020)
• Page Start: 1760
• Page End: 1763
• Publication Date: 2020-01-06
• Subjects: Aspergillus -- aspergillosis -- influenza -- intensive care -- emerging infections; Communicable diseases -- Periodicals; 616.905
• DOI: 10.1093/cid/ciaa007
• Languages: English
• ISSNs: 1058-4838

Abstract

Abstract: From 2014–2019, invasive pulmonary aspergillosis complicated 7.2% (0–23.1% in different influenza seasons) of cases of influenza-associated respiratory failure in Edmonton, Alberta. Disease outcomes ranged from survival without therapy to death despite antifungals. Clinician vigilance, longitudinal local surveillance, and refined criteria to identify patients requiring therapy are needed.