Aluminium salt-based antiperspirant coated prosthesis liners do not suppress local sweating during moderate intensity exercise in hot and temperate conditions. Issue 12 (December 2020)

• Record Type: Journal Article
• Authors: Morris, Nathan B.; Jay, Ollie
• Is Part Of: Journal of science and medicine in sport. Volume 23:Issue 12(2020)
• Page Start: 1128
• Page End: 1133
• Publication Date: 2020-12
• Subjects: Residual limb hyperhidrosis -- Amputation -- Compensatory hyperhidrosis -- Amputee -- Paralympic sport; Sports sciences -- Periodicals; Sports medicine -- Periodicals; Exercise -- Physiological aspects -- Periodicals; Sports -- physiology -- Periodicals; Sports Medicine -- Periodicals; Sportgeneeskunde; 617.102705
• DOI: 10.1016/j.jsams.2020.05.012
• Languages: English
• ISSNs: 1440-2440

Abstract

Abstract: Objective: To determine whether coating prosthesis liners with a 5% aluminium zirconium tetrachlorohydrate antiperspirant solution (AZCH) reduces local sweating on the thigh. Design: Double-blinded counter-balanced crossover design Methods: Fourteen able-bodied participants (age: 28 ± 5 y; body mass: 73.9 ± 7.9 kg, height: 1.73 ± 0.09 m; peak oxygen consumption [VO2peak ]: 50.7 ± 9.1 mlO2 ⋅ kg −1 ⋅ min −1 ) simultaneously wore a prosthesis liner on each leg, one treated with AZCH and one untreated, for four days prior to running at 50% of VO2peak for 60 min in a temperate (23.7 ± 0.7 °C and 42.2 ± 2.6% relative humidity) or hot (34.0 ± 1.6 °C and 40.8 ± 6.1% relative humidity) environment. Rectal temperature (Tre ) and whole-body sweat rates (WBSR) were measured to characterize thermal strain. Local sweat rate (LSR) was measured bilaterally underneath the liners, continuously, and heat-activated-sweat gland density (HASGD) was measured bilaterally every 15 min. Results: In temperate condition, the mean change in Tre was 1.2±0.4 °C and WBSR was 723 ± 129 g⋅ h −1, whereas in the hot condition, change in Tre was 1.2±0.5 °C and WBSR was 911 ± 231 g⋅ h −1 . In the temperate condition, AZCH treatment did not alter LSR (treated: 0.50±0.17 mg·cm –2 min –1, untreated: 0.50±0.17 mg·cm –2 min –1 ; P = 0.87) or HASGD (treated: 54±14 glands·cm –2, untreated 55±14 glands·cm –2 ; P = 0.38). In the hot condition, AZCH treatment paradoxically increased LSR (treated: 0.88 ± 0.38 mg·cm –2 min –1, untreated: 0.74 ± 0.28 mg·cm –2 min –1 ; P = 0.04) but not HASGD (treated: 52 ± 17 glands·cm –2, untreated: 48 ± 19 glands·cm –2 ; P = 0.77). Conclusion: These results indicate coating prosthesis liners with 5% AZCH is ineffective at reducing local sweating.