Occipital intracerebral hemorrhage—clinical characteristics, outcome, and post‐ICH epilepsy. (15th July 2020)

• Record Type: Journal Article
• Authors: Räty, Silja; Sallinen, Hanne; Virtanen, Pekka; Haapaniemi, Elena; Wu, Teddy Y; Putaala, Jukka; Meretoja, Atte; Tatlisumak, Turgut; Strbian, Daniel
• Is Part Of: Acta neurologica Scandinavica. Volume 143:Number 1(2021)
• Page Start: 71
• Page End: 77
• Publication Date: 2020-07-15
• Subjects: cerebral hemorrhage -- epilepsy -- occipital lobe -- outcome -- visual fields; Neurology -- Periodicals; 616.8
• DOI: 10.1111/ane.13303
• Languages: English
• ISSNs: 0001-6314

Abstract

Abstract : Objectives: Posterior location affects the clinical presentation and outcome of ischemic stroke, but little is known about occipital intracerebral hemorrhage (ICH). We studied non‐traumatic occipital ICH phenotype, outcome, and post‐ICH epilepsy. Materials and Methods: Occipital ICH patients were retrospectively identified from the Helsinki ICH Study registry of 1013 consecutive ICH patients treated in our tertiary center in 2005‐2010. They were compared to non‐occipital ICH patients to evaluate the effect of location on functional outcome at discharge (dichotomized modified Rankin Scale, mRS), 3‐ and 12‐month mortality, and incidence of epilepsy. Results: We found 19 occipital ICH patients (5.3% of lobar and 1.9% of all ICH). Compared to non‐occipital lobar ICHs, they were younger (median age 63 vs 71 years, P = .007) and had lower National Institutes of Health Stroke Scale on admission (1 vs 8, P < .001), smaller hematoma volume (6.3 vs 17.7 ML, P = .008), and more frequently structural etiology underlying the ICH (26% vs 7%, P = .01). Mortality at both 3 and 12 months was 6%, whereas 84% reached favorable outcome (mRS 0‒2) at discharge. Occipital location was associated with favorable outcome at discharge in lobar ICH (OR 11.02, 95% CI 1.55‒78.20). Incidence of post‐ICH epilepsy (median follow‐up 2.7 years) was 18%, equaling to that of non‐occipital lobar ICH. Conclusions: Occipital ICH patients are younger, have less severe clinical presentation, smaller hematoma volume, more often structural etiology, and better outcome than other ICH patients. They exhibit a similar risk of epilepsy as non‐occipital ICHs.