Design, Synthesis and Biological Evaluation of Stilbene Derivatives Containing a 1, 3‐Benzodioxole Moiety. Issue 43 (18th November 2020)

• Record Type: Journal Article
• Authors: Song, Di; Cao, Xiufang; Huang, Wenbo; Ke, Shaoyong
• Is Part Of: ChemistrySelect. Volume 5:Issue 43(2020)
• Page Start: 13563
• Page End: 13568
• Publication Date: 2020-11-18
• Subjects: Stilbene -- 1, 3-Benzodioxole -- Antifungal activity -- Insecticide activity -- Cytotoxicity activity; Chemistry -- Periodicals; 540.5
• DOI: 10.1002/slct.202003860
• Languages: English
• ISSNs: 2365-6549

Abstract

Abstract: Stilbene is an important class of biologically active metabolites with diarylethene scaffold, and which have a broad range of biological activities as the lead for drug discovery. In this study, a novel series of stilbene derivatives bearing 1, 3‐benzodioxole moiety was designed and synthesized via a convenient method with good to excellent yields, and their structures were characterized by 1 H NMR, 13 C NMR, ESI‐MS spectrum. These newly prepared compounds were evaluated for their potential biological activities including fungicidal, insecticidal, and cytotoxic activities. Abstract : A series of novel stilbene derivatives bearing 1, 3‐benzodioxole moiety were designed and synthesized, and their potential biological activities including fungicidal, insecticidal, and cytotoxic activities were evaluated.