Incidence of Tuberculosis During the First Year of Antiretroviral Treatment in West African HIV-Infected Adults. (2nd June 2020)

• Record Type: Journal Article
• Authors: Tchakounte Youngui, Boris; Coffie, Patrick; Messou, Eugène; Poda, Armel; Fortes Deguenonvo, Louise; Hawerlander, Denise; Minga, Albert; Balestre, Eric; Dabis, François; Marcy, Olivier
• Is Part Of: Open forum infectious diseases. Volume 7:Number 6(2020)
• Publication Date: 2020-06-02
• Subjects: antiretroviral treatment -- HIV -- incidence -- tuberculosis -- West Africa; Communicable diseases -- Periodicals; Medical microbiology -- Periodicals; Infection -- Periodicals; 616.9
• DOI: 10.1093/ofid/ofaa203
• Languages: English
• ISSNs: 2328-8957

Abstract

Abstract: We estimated tuberculosis incidence during the first year on antriretroviral therapy without isoniazid-preventive treatment in 6938 West African HIV-infected adults at 3.33 cases per 100 person-years (95% CI, 2.85–3.80). In multivariate Poisson models, sites in Cote d'Ivoire, male gender, low body mass index, low hemoglobin, low CD4 count, and young age were significantly associated with higher incidence.