"What" and "How": A New Perspective for Understanding Unawareness in Alzheimer's Disease Through a Combination of Two Perspectives. (5th June 2020)

• Record Type: Journal Article
• Authors: Mayelle, Amandine; El Haj, Mohamad; Antoine, Pascal
• Is Part Of: American journal of Alzheimer's disease & other dementias. Volume 35(2020)
• Publication Date: 2020-06-05
• Subjects: Alzheimer's disease -- anosognosia -- awareness -- identity -- phenomenology -- self-assessment; Alzheimer's disease -- Periodicals; Dementia -- Periodicals; Alzheimer's disease -- Patients -- Care -- United States -- Periodicals; 616.83
• DOI: 10.1177/1533317520925333
• Languages: English
• ISSNs: 1533-3175

Abstract

Objectives: Assessments of unawareness in Alzheimer's disease mainly focus on the objects (the "what") of unawareness. A recent person-centered approach proposes to also assess the processes (the "how"). The present study combines 2 approaches to understand this heterogeneity in assessments of unawareness. Method: We recruited 46 participants from 8 nursing homes. They underwent a semi-structured interview and were assessed using a prediction–performance paradigm. Spearman correlations were calculated, and generalized additive models were established. Results: The 2 approaches are associated through cognitive deficits, confrontation with difficulties and identity changes. Objects (the what), mechanisms, and modes of expression (the how) explain at least 29.6% of the variance of unawareness. Conclusions: Unawareness is more than simply being unaware of something; it is a synergy between the objects and processes of arousal and expression. Moreover, unawareness extends beyond the disease to include the self. Considering the entire person seems to be necessary.