A fast and easy-to-learn technique for liver resection in a porcine model. Issue 2 (February 2021)

• Record Type: Journal Article
• Authors: Majlesara, Ali; Krause, Jürgen; Khajeh, Elias; Ghamarnejad, Omid; Gharabaghi, Negin; Tinoush, Parham; Mohammadi, Sara; Al-Saeedi, Mohammed; Mehrabi, Arianeb; Golriz, Mohammad
• Is Part Of: Journal of international medical research. Volume 49:Issue 2(2021)
• Publication Date: 2021-02
• Subjects: Anatomy -- extended hepatectomy -- liver resection -- porcine -- stapler -- resection technique; Medicine -- Periodicals; Pharmacology -- Periodicals; 610.5
• DOI: 10.1177/0300060521990219
• Languages: English
• ISSNs: 0300-0605

Abstract

Objective: Despite the recent advances in surgical techniques and perioperative care, liver resection (especially extended hepatectomy) is still a high-risk procedure with considerable morbidity and mortality. Experimental large animal models are the best option for studies in this regard. The present study was performed to present an easy-to-learn, fast, and multipurpose model of liver resection in a porcine model. Method: Stepwise liver resections (resection of segments II/III, IVa/IVb, and VIII/IV) were performed in eight pigs with intraoperative monitoring of hemodynamic parameters. The technical aspects, tips, and tricks of this method are explained in detail. Results: Based on the specific anatomical characteristics of the porcine liver, all resection types including segmental resection, hemihepatectomy, and extended hepatectomy could be performed in one animal in an easy-to-learn and fast technique. All animals were hemodynamically stable following stepwise liver resection. Conclusion: Stepwise liver resection using stapler in a porcine model is a fast and easy-to-learn method with which junior staff and research fellows can perform liver resection up to extended hepatectomy under stable conditions.