Looking for central tendencies in the conformational freedom of proteins using NMR measurements. (16th January 2017)
- Record Type:
- Journal Article
- Title:
- Looking for central tendencies in the conformational freedom of proteins using NMR measurements. (16th January 2017)
- Main Title:
- Looking for central tendencies in the conformational freedom of proteins using NMR measurements
- Authors:
- Clarelli, Fabrizio
Sgheri, Luca - Abstract:
- Abstract: We study the conformational freedom of a protein made by two rigid domains connected by a flexible linker. The conformational freedom is represented as an unknown probability distribution on the space of allowed states. A new algorithm for the calculation of the maximum allowable probability is proposed, which can be extended to any type of measurements. In this paper we use pseudo contact shifts and residual dipolar coupling. We reconstruct a single central tendency in the distribution and discuss in depth the results.
- Is Part Of:
- Inverse problems. Volume 33:Number 2(2017:Feb.)
- Journal:
- Inverse problems
- Issue:
- Volume 33:Number 2(2017:Feb.)
- Issue Display:
- Volume 33, Issue 2 (2017)
- Year:
- 2017
- Volume:
- 33
- Issue:
- 2
- Issue Sort Value:
- 2017-0033-0002-0000
- Page Start:
- Page End:
- Publication Date:
- 2017-01-16
- Subjects:
- protein folding -- paramagnetic NMR -- underdetermined problems
Inverse problems (Differential equations) -- Periodicals
515.357 - Journal URLs:
- http://iopscience.iop.org/0266-5611 ↗
http://ioppublishing.org/ ↗ - DOI:
- 10.1088/1361-6420/aa54ea ↗
- Languages:
- English
- ISSNs:
- 0266-5611
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 15004.xml