Back Cover: Selective Sensing of Proteins Using Aptamer Functionalized Nanopore Extended Field‐Effect Transistors (Small Methods 11/2020). Issue 11 (12th November 2020)

• Record Type: Journal Article
• Authors: Ren, Ren; Wang, Xiaoyi; Cai, Shenglin; Zhang, Yanjun; Korchev, Yuri; Ivanov, Aleksandar P.; Edel, Joshua B.
• Is Part Of: Small methods. Volume 4:Issue 11(2020)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2020-11-12
• Subjects: aptamers -- ionic field‐effect transistors -- nanopores -- single‐molecule protein sensing; Nanotechnology -- Methodology -- Periodicals; Nanotechnology -- Periodicals; Periodicals; 620.5028
• DOI: 10.1002/smtd.202070044
• Languages: English
• ISSNs: 2366-9608

Abstract

Abstract : In article number 2000356, Aleksandar P. Ivanov, Joshua Edel, and co‐workers, develop a new device—aptamer functionalized nanopore extended field‐effect transistor (nexFET)—to detect proteins at the single‐molecule level with high sensitivity and selectivity. With this aptamer modified nexFET, the gate voltage facilitates single‐molecule protein detection at low concentrations (pM) with improved signal‐to‐noise, higher capture rate, and lower translocating speed.