Indirect detection of intermediate in decarboxylation reaction of phenylglyoxylic acid by hyperpolarized 13C NMR. Issue 95 (13th November 2020)

• Record Type: Journal Article
• Authors: Kim, Jiwon; Kim, Yaewon; Luu, Quy Son; Kim, Jihyun; Qi, Chang; Hilty, Christian; Lee, Youngbok
• Is Part Of: Chemical communications. Volume 56:Issue 95(2020)
• Page Start: 15000
• Page End: 15003
• Publication Date: 2020-11-13
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/d0cc06331b
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : Nuclear spin hyperpolarization is used to enhance NMR signals for observation of chemical reactions in real-time. Here, we introduce a blind saturation technique, which enables the indirect detection of otherwise unobservable reaction intermediates. Abstract : The decarboxylation reaction of phenylglyoxylic acid with hydrogen peroxide is studied by real-time hyperpolarized carbon-13 nuclear magnetic resonance ( 13 C NMR) spectroscopy at room temperature. A non-observable reaction intermediate is identified using blind selective saturation pulses in the expected chemical shift range, thereby revealing information on the reaction mechanism.