Treatment options for sclerosing angiomatoid nodular transformation of spleen. Issue 11 (November 2020)

• Record Type: Journal Article
• Authors: Jin, Yanwen; Hu, Hajie; Regmi, Parbatraj; Li, Fuyu; Cheng, Nansheng
• Is Part Of: HPB. Volume 22:Issue 11(2020)
• Page Start: 1577
• Page End: 1582
• Publication Date: 2020-11
• Subjects: Liver -- Diseases -- Periodicals; Biliary tract -- Diseases -- Periodicals; Pancreas -- Diseases -- Periodicals; 616.362005
• DOI: 10.1016/j.hpb.2020.01.014
• Languages: English
• ISSNs: 1365-182X

Abstract

Abstract: Background: To summarise the clinical features of Sclerosing angiomatoid nodular transformation (SANT) of the spleen and to compare the efficacy of three different surgical treatments. Methods: We performed a retrospective analysis of patients with SANT of spleen treated at our center from 2009 to 2018. We compared the efficacy and safety of three different types of surgical procedures. ANOVA and the chi-square test were used for statistical analysis. Results: A total of 37 patients were included. Most (35/37; 94.6%) were asymptomatic. A number presented as obscure boundary lesions such that malignancy could not be excluded. Open splenectomy was performed for 12 patients, laparoscopic splenectomy for 12 patients and laparoscopic partial splenectomy for 13 patients. Operation time ( P = 0.355), blood loss ( P = 0.135), length of hospital stay after operation ( P = 0.271) and postoperative complications ( P = 0.502) were comparable between the three groups. Duration of drainage tube placement was significantly longer in laparoscopic partial splenectomy patients ( P = 0.006). Peak platelet count after operation was significantly lower in laparoscopic partial splenectomy patients ( P < 0.001). Conclusion: Laparoscopic partial splenectomy appears to be a technically feasible and therapeutically effective approach for SANT.