Far-red switching DNA probes for live cell nanoscopy. Issue 94 (3rd November 2020)
- Record Type:
- Journal Article
- Title:
- Far-red switching DNA probes for live cell nanoscopy. Issue 94 (3rd November 2020)
- Main Title:
- Far-red switching DNA probes for live cell nanoscopy
- Authors:
- Bucevičius, Jonas
Gilat, Tanja
Lukinavičius, Gražvydas - Abstract:
- Abstract : Blinking far-red hydroxymethyl silicon-rhodamine and Hoechst conjugates for chromatin nanoscopy in live cells. Abstract : Herein we present DNA probes composed of Hoechst 33258 and spontaneously blinking far-red hydroxymethyl silicon-rhodamine (HMSiR). The best performing probe, 5-HMSiR-Hoechst, contains the 5′-regioisomer, shows ∼400-fold fluorescence increase upon DNA binding and is compatible with wash-free single molecule localization and 3D stimulated emission depletion microscopy of chromatin nanostructures in living cells.
- Is Part Of:
- Chemical communications. Volume 56:Issue 94(2020)
- Journal:
- Chemical communications
- Issue:
- Volume 56:Issue 94(2020)
- Issue Display:
- Volume 56, Issue 94 (2020)
- Year:
- 2020
- Volume:
- 56
- Issue:
- 94
- Issue Sort Value:
- 2020-0056-0094-0000
- Page Start:
- 14797
- Page End:
- 14800
- Publication Date:
- 2020-11-03
- Subjects:
- Chemistry -- Periodicals
540 - Journal URLs:
- http://pubs.rsc.org/en/journals/journalissues/cc ↗
http://www.rsc.org/ ↗ - DOI:
- 10.1039/d0cc06759h ↗
- Languages:
- English
- ISSNs:
- 1359-7345
- Deposit Type:
- Legaldeposit
- View Content:
- Available online (eLD content is only available in our Reading Rooms) ↗
- Physical Locations:
- British Library DSC - 3139.350000
British Library DSC - BLDSS-3PM
British Library STI - ELD Digital store - Ingest File:
- 14856.xml