Expanding the capillary electrophoresis-based glucose unit database of the GUcal app. (12th December 2019)

• Record Type: Journal Article
• Authors: Jarvas, Gabor; Szigeti, Marton; Campbell, Matthew P; Guttman, Andras
• Is Part Of: Glycobiology. Volume 30:Number 6(2020)
• Page Start: 362
• Page End: 364
• Publication Date: 2019-12-12
• Subjects: capillary electrophoresis -- database -- glucose unit -- N-glycan -- structure identification; Glycoproteins -- Periodicals; Glycolipids -- Periodicals; Glycoconjugates -- Periodicals; 572.567
• DOI: 10.1093/glycob/cwz102
• Languages: English
• ISSNs: 0959-6658

Abstract

Abstract: GUcal is a standalone application for automatically calculating the glucose unit (GU) values for separated N -glycan components of interest in an electropherogram and suggests their tentative structures by utilizing an internal database. We have expanded the original database of GUcal by integrating all publicly available capillary electrophoresis (CE) data in the GlycoStore collection (https://www.glycostore.org ) and with in-house measured GU values. The GUcal app is freely available online (https://www.gucal.hu ) and readily facilitates CE-based high throughput GU value determination for first line structural elucidation.