Photoimmunotherapy: Artificial Metalloprotein Nanoanalogues: In Situ Catalytic Production of Oxygen to Enhance Photoimmunotherapeutic Inhibition of Primary and Abscopal Tumor Growth (Small 46/2020). Issue 46 (19th November 2020)

• Record Type: Journal Article
• Authors: Huang, Rongtao; Ding, Zhaoyang; Jiang, Bang‐Ping; Luo, Zilan; Chen, Ting; Guo, Zhengxi; Ji, Shi‐Chen; Liang, Hong; Shen, Xing‐Can
• Is Part Of: Small. Volume 16:Issue 46(2020)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2020-11-19
• Subjects: in situ catalysis -- metalloprotein nanoanalogues -- photoimmunotherapy -- ruthenium oxides -- tumor hypoxia; Nanotechnology -- Periodicals; Nanoparticles -- Periodicals; Microtechnology -- Periodicals; 620.5
• DOI: 10.1002/smll.202070254
• Languages: English
• ISSNs: 1613-6810

Abstract

Abstract : In article number 2004345, Bang‐Ping Jiang, Xing‐Can Shen, and co‐workers develop one type of brand‐new artificial metalloprotein nanoanalogues for enhanced photoimmunotherapy via reasonably integrating "phototherapy‐enzymatic" RuO2 and model antigen ovalbumin. This ushers a prospect of concurrently enhancing photodynamic therapy and reversing the immunosuppressive tumor microenvironment by in situ catalyzing overexpressed H2 O2 to produce O2 .