The Mechanism of the Intramolecular Hydrocarbyl Metathesis within a Planar Triruthenium Cluster: Combining Core Flexibility with Hydride Mobility. Issue 61 (28th September 2020)

• Record Type: Journal Article
• Authors: Castillo, Carmen E.; Algarra, Andrés G.
• Is Part Of: Chemistry. Volume 26:Issue 61(2020)
• Page Start: 13880
• Page End: 13889
• Publication Date: 2020-09-28
• Subjects: C−H activation -- density functional calculations -- metathesis -- reaction mechanisms -- ruthenium; Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.202001539
• Languages: English
• ISSNs: 0947-6539

Abstract

Abstract: The transition metal catalysed formation and cleavage of C−C bonds is of utmost importance in synthetic chemistry. While most of the existing homogeneous catalysts are mononuclear, knowledge of the behaviour of polynuclear species is much more limited. By using computational methods, here we shed light into the mechanistic details of the thermally‐induced isomerization of Cp*3 Ru3 (μ‐H)2 (μ3 ‐η 2 ‐pentyne)(μ3 ‐pentylidyne) (2 ) into Cp*3 Ru3 (μ‐H)2 (μ3 ‐η 2 ‐octyne)(μ3 ‐ethylidyne) (3 ), a process that involves the migration of a C3 fragment between the hydrocarbyl ligands and across the plane formed by the three Ru centres. Our results show this to be a complex transformation that comprises of five individual rearrangements in an A → B → A → B → A order. Each so‐called rearrangement A consists of the CH migration from the μ3 ‐η 2 ‐alkyne into the μ3 ‐alkylidine ligand in the other side of the Ru3 plane. This process is facilitated by the cluster's ability to adopt open‐core structures in which one Ru−Ru bond is broken and a new C−C bond is formed. In contrast, rearrangements B do not involve the formation or cleavage of C−C bonds, nor do they require the opening of the cluster core. Instead, they consist of the isomerization of the μ3 ‐η 2 ‐alkyne and μ3 ‐alkylidyne ligands on each side of the triruthenium plane into μ3 ‐alkylidyne and μ3 ‐η 2 ‐alkyne, respectively. Such transformation implies the migration of three H atoms within the hydrocarbyl ligands, and in this case, it is aided by the cluster's ability to behave as a H reservoir. All in all, this study highlights the plasticity of these Ru3 clusters, whereby Ru−Ru, Ru−C, Ru−H, C−C, and C−H bonds are formed and broken with surprising ease. Abstract : Flexible and mobile : The thermally induced isomerization of ruthenium hydrocarbyl 2 into 3 involves the formal migration of a C3 fragment between the hydrocarbyl ligands and across the plane formed by the three Ru centres. By using computational methods, herein we answer to the main mechanistic questions about this complex transformation that implies the cleavage and formation of Ru−Ru, Ru−C, Ru−H, C−C and C−H bonds.