Front Cover: Glucose as an Eco‐Friendly Reductant in a One‐Pot Synthesis of 2, 3‐Dihydroquinazolin‐4(1H)‐ones (Eur. J. Org. Chem. 41/2020). Issue 41 (30th September 2020)

• Record Type: Journal Article
• Authors: dos Santos, Thiago; Grundke, Caroline; Lucas, Tobias; Großmann, Luca; Clososki, Giuliano Cesar; Opatz, Till
• Is Part Of: European journal of organic chemistry. Issue 41(2020)
• Page Start: 6400
• Page End: 6400
• Publication Date: 2020-09-30
• Subjects: Chemistry, Organic -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Bioorganic chemistry -- Periodicals; Chemistry, Physical organic -- Periodicals; 547
• DOI: 10.1002/ejoc.202001285
• Languages: English
• ISSNs: 1434-193X

Abstract

Abstract : The Front Cover shows the Iguaçu cascades in Brazil, that illustrate the reaction cascade consisting of nitrile hydration, nitro‐reduction, imine formation, and cyclization which takes place when glucose is employed as a mild reductant in alkaline aqueous medium for the synthesis of 2, 3‐dihydroquinazolin‐4(1 H )‐ones. The different intermediates are placed along the path of the falling water. More information can be found in the Communication by G. C. Clososki, T. Opatz et al.