Catalytic O2 activation with synthetic models of α-ketoglutarate dependent oxygenases. Issue 92 (5th November 2020)

• Record Type: Journal Article
• Authors: Sánchez-Eguía, Brenda N.; Serrano-Plana, Joan; Company, Anna; Costas, Miquel
• Is Part Of: Chemical communications. Volume 56:Issue 92(2020)
• Page Start: 14369
• Page End: 14372
• Publication Date: 2020-11-05
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/d0cc05942k
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : An iron complex with a tridentate 1, 4, 7-triazacyclononane ligand mimics structural and functional features of α-ketoglutarate (α-KG) dependent enzymes, and engages in catalytic O2 activation coupled to α-KG decarboxylation and sulfide oxygenation. Abstract : An iron complex bearing the facially capping tridentate 1, 4, 7-triazacyclononane ligand mimics structural and functional features of alpha-ketoglutarate (α-KG) dependent enzymes, and engages in enzyme-like catalytic O2 activation coupled to α-ketoacid decarboxylation, oxygenating sulfides. This system constitutes a rare case of non-enzymatic catalytic O2 activation, cycling between Fe II and Fe IV (O).