Enhancing the selectivity of optical sensors using synthetic transmembrane ion transporters. Issue 92 (4th November 2020)

• Record Type: Journal Article
• Authors: Marshall, Sarah R.; Singh, Anmol; Wagner, Jacqueline N.; Busschaert, Nathalie
• Is Part Of: Chemical communications. Volume 56:Issue 92(2020)
• Page Start: 14455
• Page End: 14458
• Publication Date: 2020-11-04
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/d0cc06437h
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : As proof-of-concept, we show that the non-selective anion sensor lucigenin can be converted to a selective iodide sensor by encapsulation into liposomes and the addition of transmembrane transporters. Abstract : Herein, we introduce a new method to optimize the properties of optical sensors, coined the transporter–liposome–fluorophore (TLF) approach. It is shown that this approach can greatly improve the selectivity of the sensor, increase the dynamic range and maintain the sensitivity of the original fluorophore.