Aminomethylation of imidazopyridines using N, N-dimethylformamide as an aminomethylating reagent under Cu(II)-catalysis. Issue 49 (3rd December 2020)

• Record Type: Journal Article
• Authors: Ghosh, Payel; Samanta, Sadhanendu; Ghosh, Sumit; Jana, Sourav; Hajra, Alakananda
• Is Part Of: Tetrahedron letters. Volume 61:Issue 49(2020)
• Publication Date: 2020-12-03
• Subjects: Aminomethylation -- Imidazopyridine -- DMF -- Cu(II)-catalysis -- Radical; Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1016/j.tetlet.2020.152581
• Languages: English
• ISSNs: 0040-4039

Abstract

Graphical abstract: Highlights: N, N -Dimethylformamide has been explored as an aminomethylating reagent. Synthesis of aminomethylated imidazo[1, 2- a ]pyridines under Cu(II)-catalysis. Selective functionalization of imidazo[1, 2- a ]pyridines at the C-3 position. Abstract: N, N -Dimethylformamide has been explored as an aminomethylating reagent in the functionalization of imidazopyridine under Cu(II)-catalysis. A library of aminomethylated imidazopyridines with broad functionalities was synthesized in good yields.