Organ‐On‐A‐Chip Systems: Human‐on‐Leaf‐Chip: A Biomimetic Vascular System Integrated with Chamber‐Specific Organs (Small 22/2020). Issue 22 (4th June 2020)

• Record Type: Journal Article
• Authors: Mao, Mao; Bei, Ho Pan; Lam, Chun Hei; Chen, Pengyu; Wang, Shuqi; Chen, Ying; He, Jiankang; Zhao, Xin
• Is Part Of: Small. Volume 16:Issue 22(2020)
• Page Start: n/a
• Page End: n/a
• Publication Date: 2020-06-04
• Subjects: cancer metastasis -- microfluidics -- organ‐on‐a‐chip -- vasculature; Nanotechnology -- Periodicals; Nanoparticles -- Periodicals; Microtechnology -- Periodicals; 620.5
• DOI: 10.1002/smll.202070124
• Languages: English
• ISSNs: 1613-6810

Abstract

Abstract : In article number 2000546, Jiankang He, Xin Zhao, and co‐workers report a human‐on‐leaf#x02010;chip system with biomimetic multiscale vasculature systems connecting vascularized organs, mimicking the complex in vivo architectures of the human cardiovascular system. The native organ‐to‐organ crosstalk is well recapitulated, implicating a strong potential for harnessing the leaf chip for circulatory‐related studies such as metastasis.