High-Resolution Imaging of Retinal Vasculitis by Flood Illumination Adaptive Optics Ophthalmoscopy: A Follow-up Study. (16th November 2020)

• Record Type: Journal Article
• Authors: Errera, Marie-Hélène; Laguarrigue, Marthe; Rossant, Florence; Koch, Edouard; Chaumette, Céline; Fardeau, Christine; Westcott, Mark; Sahel, José-Alain; Bodaghi, Bahram; Benesty, Jonathan; Paques, Michel
• Is Part Of: Ocular immunology and inflammation. Volume 28:Number 8(2020)
• Page Start: 1171
• Page End: 1180
• Publication Date: 2020-11-16
• Subjects: adaptive optics -- posterior uveitis -- retina -- uveitis -- retinal vasculitis; Eye -- Diseases -- Immunological aspects -- Periodicals; Eye -- Inflammation -- Periodicals; 617.7
• DOI: 10.1080/09273948.2019.1646773
• Languages: English
• ISSNs: 0927-3948

Abstract

ABSTRACT: Purpose : To monitor perivascular sheathing during the course of retinal vasculitis by flood illumination adaptive optics ophthalmoscopy (AOO). Methods : Perivenous sheathing and venous diameters were quantitatively analyzed by semi-automatic segmentation of AOO images in 12 eyes of treatment-naive patients with retinal vasculitis. Results : The width of venous sheathing ranged from 45 to 225 µm (mean 101.0 µm ± 54.3). In 10 cases, the underlying vein showed focal narrowing (mean ± SD 14% ± 10). Focal narrowing of arteries was also present in one eye. At presentation, width of sheathing and vessel diameters were not correlated with fluorescein leakage. During follow-up, 5 eyes showed an increase in vein diameter or resolution of narrowing and in 10 eyes a thinning of vascular sheathing was observed ( p = .003). Conclusions : Perivenous sheathing may be quantitatively analyzed and monitored by AOO. AOO may therefore contribute to monitor vascular sheathing during posterior uveitis.