New flavonoids from the fruits of Cornus mas, Cornaceae. (March 2015)

• Record Type: Journal Article
• Authors: Rudrapaul, Prasenjit; Kyriakopoulos, Anthony M.; De, Utpal Chandra; Zoumpourlis, Vassilis; Dinda, Biswanath
• Is Part Of: Phytochemistry letters. Volume 11(2015:Mar.)
• Page Start: 292
• Page End: 295
• Publication Date: 2015-03
• Subjects: Cornus mas -- Flavonoids -- β-Hydroxychalcone -- Flavanone; Botanical chemistry -- Periodicals; Chimie végétale -- Périodiques; 572.205
• DOI: 10.1016/j.phytol.2015.01.011
• Languages: English
• ISSNs: 1874-3900

Abstract

Graphical abstract: Highlights: Chemical constituents of Cornus mas fruits. Isolation of two new compounds, β-hydroxychalcone and flavanone. New compounds were characterized by spectroscopic methods. Abstract: One new β-hydroxychalcone, 4-acetoxy-5, 2′, 4′, 6′, β-pentahydroxy-3-methoxychalcone (1 ), one new flavanone, 7, 3′-dihydroxy-5, 4′-dimethoxyflavanone (2 ) and seven known compounds, 2 R, 3 R - trans -aromadendrin (3 ), naringenin-7- O -methylether (4 ), myricetin (5 ), quercetin-3- O -rutinoside (6 ), ursolic acid (7 ), gallic acid (8 ) and d -glucose (9 ) were isolated from the methanolic fruit extract of Cornus mas L. (= Cornus mascula L.), Cornaceae. The structures of the new compounds were elucidated on the basis of extensive spectroscopic methods, including 2D NMR experiments and of known compounds by comparison of physical and spectral data with literature.