Direct and Selective Synthesis of Adipic and Other Dicarboxylic Acids by Palladium‐Catalyzed Carbonylation of Allylic Alcohols. Issue 46 (15th September 2020)

• Record Type: Journal Article
• Authors: Yang, Ji; Liu, Jiawang; Ge, Yao; Huang, Weiheng; Neumann, Helfried; Jackstell, Ralf; Beller, Matthias
• Is Part Of: Angewandte Chemie international edition. Volume 59:Issue 46(2020)
• Page Start: 20394
• Page End: 20398
• Publication Date: 2020-09-15
• Subjects: adipic acid -- allylic alcohols -- carbonylation -- carboxylic acids -- palladium; Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.202008916
• Languages: English
• ISSNs: 1433-7851

Abstract

Abstract: A general and direct synthesis of dicarboxylic acids including industrially important adipic acid by palladium‐catalyzed dicarbonylation of allylic alcohol is reported. Specifically, the combination of PdCl2 and a bisphosphine ligand (HeMaRaphos) promotes two different carbonylation reactions with high activity and excellent selectivity. Abstract : A general direct and selective synthesis of adipic acid and other dicarboxylic acids by palladium‐catalyzed dicarbonylation of allylic alcohol is reported. Specifically, the combination of PdCl2 and a bisphosphine ligand (HeMaRaphos) promotes two different carbonylation reactions as well as olefin isomerization with high activity.