Spororrminone A and 2-epi-spororrminone A, two new chromones from an endolichenic fungus Sporormiella irregularis. Issue 21 (1st November 2020)

• Record Type: Journal Article
• Authors: Huang, Mei-Juan; Li, Yan-Jun; Tang, Jia; Chen, Guo-Dong; Hu, Dan; Xu, Wei; Guo, Liang-Dong; Yao, Xin-Sheng; Gao, Hao
• Is Part Of: Natural product research. Volume 34:Issue 21(2020)
• Page Start: 3117
• Page End: 3124
• Publication Date: 2020-11-01
• Subjects: Chromones -- 2-(5-oxotetrahydrofuran-2-yl) chromones -- spororrminone A -- 2-epi-spororrminone A -- Sporormiella irregularis -- endolichenic fungus; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2019.1610758
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: Two new chromones, spororrminone A (1, ( S )-5-hydroxy-2-methyl-4-oxo-2-(( S )-5-oxotetrahydrofuran-2-yl)chroman-7-carboxylic acid) and 2- epi -spororrminone A (2, ( R )-5-hydroxy-2-methyl-4-oxo-2-(( S )-5-oxotetrahydrofuran-2-yl)chroman-7-carboxylic acid), were isolated from an EtOAc extract of an endolichenic fungal strain Sporormiella irregularis (No. 71-11-4-1). The structures of these compounds were identified by spectroscopic analyses. The absolute configuration of 1 was established by single-crystal X-ray diffraction. Spororrminone A (1 ) and 2- epi -spororrminone A (2 ) represent the first examples of 2-(5-oxotetrahydrofuran-2-yl) chromones with 7-carboxylic group. Graphical Abstract: