One new benzophenone and one new 1, 3-diphenylpropane from the fibrous roots of Anemarrhena asphodeloides Bge. and their cytotoxicity. Issue 21 (1st November 2020)

• Record Type: Journal Article
• Authors: Liao, Zhen-Dong; Chen, Fang-Fang; Xu, Feng-Qing; Zhang, Wei; Ren, Ya-Shuo; Wang, Can-Can; Wu, De-Ling
• Is Part Of: Natural product research. Volume 34:Issue 21(2020)
• Page Start: 3054
• Page End: 3060
• Publication Date: 2020-11-01
• Subjects: Benzophenone -- 1, 3-diphenylpropane -- Anemarrhena asphodeloides Bge. -- cytotoxicity; Natural products -- Periodicals; Natural products -- Research -- Periodicals; Biological Factors -- Periodicals; Biological Products -- Periodicals; 547
• DOI: 10.1080/14786419.2019.1607856
• Languages: English
• ISSNs: 1478-6419

Abstract

Abstract: One new benzophenone (1) and one new 1, 3-diphenylpropane (2) were obtained from the fibrous roots of Anemarrhena asphodeloides Bge. Their structures were determined by comprehensive 1D, 2D NMR and HRESIMS data. By comparing the calculated ECD curves and OR with the experimental data the absolute configurations were determined. The antitumor activity of all isolates was evaluated against two human hepatoma carcinoma cells (HepG2 and Hep3B) in vitro. The results demonstrated that compound 1 and 2 showed potent cytotoxicity against HepG2 and Hep3B cells. Abstract :