Copper-catalyzed borylative cyclization of γ, δ-unsaturated aromatic oxime esters to (borylmethyl)pyrrolidines. Issue 21 (25th September 2020)

• Record Type: Journal Article
• Authors: Zhang, Youcan; Wu, Xiao-Feng
• Is Part Of: Organic chemistry frontiers. Volume 7:Issue 21(2020)
• Page Start: 3382
• Page End: 3386
• Publication Date: 2020-09-25
• Subjects: Chemistry, Organic -- Periodicals; 547.005
• DOI: 10.1039/d0qo01064b
• Languages: English
• ISSNs: 2052-4110

Abstract

Abstract : An efficient copper-catalyzed aminoborylation of γ, δ-unsaturated aromatic oxime esters with bis(pinacolato)diboron has been developed. A variety of α-(borylmethyl)pyrrolidine derivatives were constructed in high yields under mild conditions. Abstract : An efficient copper-catalyzed aminoborylation of γ, δ-unsaturated aromatic oxime esters with bis(pinacolato)diboron has been developed. A variety of α-(borylmethyl)pyrrolidine derivatives were constructed in high yields under mild conditions. Notably, examples of converting the obtained aminoborylated product, including cycloaddition, oxidation, and coupling reactions, have been given as well.