Automated micro insulin dispenser system based on the model predictive control algorithm. (12th January 2021)

• Record Type: Journal Article
• Authors: Patra, Akshaya Kumar; Nanda, Anuja
• Is Part Of: International journal of advanced mechatronic systems. Volume 8:Number 4(2020)
• Page Start: 144
• Page End: 154
• Publication Date: 2021-01-12
• Subjects: diabetes mellitus -- plasma glucose level -- micro-insulin dispenser -- MID -- Laguerre functions -- MPC/LF; Mechatronics -- Periodicals; 629.89
• Languages: English
• ISSNs: 1756-8412

Abstract

During the past few decades, optimal control of blood glucose (BG) concentration with adequate feedback loop has been of ample importance for type-I diabetes mellitus (TIDM) patients as far as an artificial pancreas (AP) realisation is concerned. Now-a-days, in addition to the BG control, the design of the micro-insulin dispenser (MID) with a robust control algorithm to regulate the other chronic clinical disorders based on prolonged medications is also quite indispensable. A novel model predictive controller with Laguerre functions (MPC/LF) has been proposed in this current work to solve the aforementioned problem. For the estimation of the MPC/LF parameters, a ninth order linearised structure of the TIDM patient with MID is taken. The productivity of the MPC/LF as to accuracy, robustness and stability has been checked through simulation. The acquired results obviously expose the better execution of the proposed strategy to control the BG level inside the normo-glycaemic extend (70-120 mg/dl). The validation of upgrading control execution of MPC/LF is exhibited by the relative outcome investigation with other well-known control procedures.