Web Tool for Navigating and Plotting SomaLogic ADAT Files. Issue 1 (8th September 2017)

• Record Type: Journal Article
• Authors: Cheung, Foo; Fantoni, Giovanna; Conner, Maria; Sellers, Brian A; Kotliarov, Yuri; Candia, Julián; Stagliano, Katherine; Biancotto, Angélique
• Is Part Of: Journal of open research software. Volume 5:Issue 1(2017)
• Publication Date: 2017-09-08
• Subjects: ADAT -- Shiny -- SOMAscan -- proteomic; Computer software -- Reusability -- Periodicals; Open source software -- Periodicals; 005
• DOI: 10.5334/jors.166
• Languages: English
• ISSNs: 2049-9647

Abstract

SOMAscan™ is a complex proteomic platform created by SomaLogic. Experimental data resulting from the assay is provided by SomaLogic in a proprietary text-based format called ADAT. This manuscript describes a user-friendly point and click open source, platform-independent software tool designed to be used for navigating and plotting data from an ADAT file. This tool was used either alone or in conjunction with other tools as a first pass analysis of the data on several different on-going research projects. We have seen a need from our experience for a web interface to the ADAT file so that users can navigate, generate plots, perform QC and conduct statistical analysis on their own data in a point and click manner. After several rounds of interacting with biologists and their requirements with respect to data analysis, we present an online interactive Shiny Web Tool for Navigating and Plotting data contained within the ADAT file. Extensive video tutorials, example data, the tool and the source code are available online.