Spontaneous remission of rectal ulcer associated with SpaceOAR® hydrogel insertion in radiotherapy for prostate cancer. Issue 6 (5th August 2020)

• Record Type: Journal Article
• Authors: Imai, Kazuto; Sakamoto, Hiromasa; Akahane, Mizuho; Nakashima, Masakazu; Fujimoto, Takeru; Aoyama, Teruyoshi
• Is Part Of: IJU case reports. Volume 3:Issue 6(2020)
• Page Start: 257
• Page End: 260
• Publication Date: 2020-08-05
• Subjects: adverse event -- prostate cancer -- radiotherapy -- rectal ulcer -- spacer; Urology -- Periodicals; Genitourinary organs -- Periodicals; Electronic journals; Periodicals; 616.6
• DOI: 10.1002/iju5.12209
• Languages: English
• ISSNs: 2577-171X

Abstract

Abstract : Introduction: The SpaceOAR ® hydrogel system separates the prostate and rectum to reduce rectal irradiation during prostate radiotherapy. However, it could induce rectal toxicity. Case presentation: A 75‐year‐old man with localized prostate cancer underwent external beam radiotherapy with the use of SpaceOAR ® System. However, postimplant magnetic resonance imaging showed hydrogel infiltration to the rectum. Three months after implantation, he complained of bowel symptoms, including bloody stool. Colonofiberscopy and computed tomography revealed a rectal ulcer associated with SpaceOAR ® hydrogel insertion. He was treated with fasting, fluid replacement, and blood transfusion. One year after implantation, complete healing was confirmed during outpatient follow‐up. Conclusion: To our knowledge, this is the first report of a rectal ulcer associated with SpaceOAR ® hydrogel insertion assessed by magnetic resonance imaging beforehand. Postimplant magnetic resonance imaging evaluation might be a useful follow‐up tool in such cases.