Disulfide Promoted C−P Bond Cleavage of Phosphoramide: "P" Surrogates to Synthesize Phosphonates and Phosphinates. Issue 21 (1st October 2020)

• Record Type: Journal Article
• Authors: Hou, Fei; Du, Xing‐Peng; Alduma, Anwar I.; Li, Zhi‐Feng; Huo, Cong‐De; Wang, Xi‐Cun; Wu, Xiao‐Feng; Quan, Zheng‐Jun
• Is Part Of: Advanced synthesis & catalysis. Volume 362:Issue 21(2020)
• Page Start: 4755
• Page End: 4760
• Publication Date: 2020-10-01
• Subjects: C−P bond cleavage -- Disulfide -- Alkyl phosphonates -- Phosphoramides -- Phosphinates; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.202000511
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract: A metal‐free C−P bond cleavage reaction is described herein. Phosphoramides, a phosphine source, can react with alcohols to produce phosphonate and phosphinate derivatives in the presence of a disulfide. P−H2, P‐alkyl, and P, P‐dialkyl phosphoramides can be used as substrates to obtain the corresponding pentavalent phosphine products. Abstract :