Photochemical O−H Functionalization Reactions of Cyclic Diazoamides. Issue 21 (17th September 2020)

• Record Type: Journal Article
• Authors: Empel, Claire; Verspeek, Dennis; Jana, Sripati; Koenigs, Rene M.
• Is Part Of: Advanced synthesis & catalysis. Volume 362:Issue 21(2020)
• Page Start: 4716
• Page End: 4722
• Publication Date: 2020-09-17
• Subjects: O−H functionalization -- cyclic diazoamides -- photochemistry -- fluorine.; Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.202000818
• Languages: English
• ISSNs: 1615-4150

Abstract

Abstract: Herein, we describe the photochemical O−H functionalization reaction of acidic alcohols with cyclic diazoamides. We studied the O−H functionalization reaction of different fluorinated and non‐fluorinated alcohols to give the corresponding ether products in high yields (43 examples, up to 97% yield). Furthermore, we performed studies to evaluate a photoexcited proton transfer reaction pathway in comparison to classic carbene transfer reactions. Abstract :