Copper and palladium co-catalyzed highly regio-selective 1, 2-hydroarylation of terminal 1, 3-dienes. Issue 88 (13th October 2020)

• Record Type: Journal Article
• Authors: Zhang, Rumeng; Li, Qifan; Zhang, Min; Chai, Sida; Duan, Yuqi; Su, Jingfei; Zhao, Qian; Zhang, Chun
• Is Part Of: Chemical communications. Volume 56:Issue 88(2020)
• Page Start: 13551
• Page End: 13554
• Publication Date: 2020-10-13
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/d0cc06007k
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : The novel and practical copper and palladium co-catalyzed 1, 2-hydroarylation of terminal 1, 3-dienes by one step reaction has been developed, which could afford a kind of versatile precursor for organic synthesis. Abstract : A practical copper and palladium co-catalyzed highly regio-selective hydroarylation of terminal 1, 3-dienes has been developed. This chemistry afforded the terminal alkenyl group containing products, which are a kind of versatile precursor for organic synthesis, from 1, 3-dienes by a practical one-step reaction. With good functional group tolerance, this protocol could be used to make a series of bio-active compounds using readily accessible starting materials. The mechanism of this reaction was explored by control experiments and kinetics studies.