Lipid based biocompatible ionic liquids: synthesis, characterization and biocompatibility evaluation. Issue 89 (19th October 2020)

• Record Type: Journal Article
• Authors: Uddin, Shihab; Chowdhury, Md. Raihan; Wakabayashi, Rie; Kamiya, Noriho; Moniruzzaman, Muhammad; Goto, Masahiro
• Is Part Of: Chemical communications. Volume 56:Issue 89(2020)
• Page Start: 13756
• Page End: 13759
• Publication Date: 2020-10-19
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1039/d0cc04491a
• Languages: English
• ISSNs: 1359-7345

Abstract

Abstract : This study reports a new series of lipid-based biocompatible ionic liquids consisting of long-chain phosphonium compound, 1, 2-dimyristoyl- sn-glycero -3-ethyl- phosphatidylcholine, as a cation and long chain fatty acids as anions. Abstract : We report a new series of lipid-based biocompatible ionic liquids (LBILs) consisting of the long-chain phosphonium compound 1, 2-dimyristoyl- sn-glycero -3-ethyl-phosphatidylcholine as the cation and the long-chain fatty acids stearic acid, oleic acid, or linoleic acid as anions. These materials were found to be completely miscible with many polar and nonpolar organic solvents as well as dispersible in water. These LBILs also exhibited excellent biocompatibility with an artificial three-dimensional human epidermis model.