Pathogens causing central-line–associated bloodstream infections in acute-care hospitals—United States, 2011–2017. (9th March 2020)

• Record Type: Journal Article
• Authors: Novosad, Shannon A.; Fike, Lucy; Dudeck, Margaret A.; Allen-Bridson, Katherine; Edwards, Jonathan R.; Edens, Chris; Sinkowitz-Cochran, Ronda; Powell, Krista; Kuhar, David
• Is Part Of: Infection control and hospital epidemiology. Volume 41:Number 3(2020)
• Page Start: 313
• Page End: 319
• Publication Date: 2020-03-09
• Subjects: Nosocomial infections -- Epidemiology -- Periodicals; Health facilities -- Sanitation -- Periodicals; Hospital buildings -- Sanitation -- Periodicals; Cross Infection -- Periodicals; Epidemiology -- Periodicals; Hospitals -- Periodicals; Infection Control -- Periodicals; 614.44
• DOI: 10.1017/ice.2019.303
• Languages: English
• ISSNs: 0899-823X

Abstract

Abstract: Objective: To describe pathogen distribution and rates for central-line–associated bloodstream infections (CLABSIs) from different acute-care locations during 2011–2017 to inform prevention efforts. Methods: CLABSI data from the Centers for Disease Control and Prevention (CDC) National Healthcare Safety Network (NHSN) were analyzed. Percentages and pooled mean incidence density rates were calculated for a variety of pathogens and stratified by acute-care location groups (adult intensive care units [ICUs], pediatric ICUs [PICUs], adult wards, pediatric wards, and oncology wards). Results: From 2011 to 2017, 136, 264 CLABSIs were reported to the NHSN by adult and pediatric acute-care locations; adult ICUs and wards reported the most CLABSIs: 59, 461 (44%) and 40, 763 (30%), respectively. In 2017, the most common pathogens were Candida spp/yeast in adult ICUs (27%) and Enterobacteriaceae in adult wards, pediatric wards, oncology wards, and PICUs (23%–31%). Most pathogen-specific CLABSI rates decreased over time, excepting Candida spp/yeast in adult ICUs and Enterobacteriaceae in oncology wards, which increased, and Staphylococcus aureus rates in pediatric locations, which did not change. Conclusions: The pathogens associated with CLABSIs differ across acute-care location groups. Learning how pathogen-targeted prevention efforts could augment current prevention strategies, such as strategies aimed at preventing Candida spp/yeast and Enterobacteriaceae CLABSIs, might further reduce national rates.