ANGI — Anorexia Nervosa Genetics Initiative. (April 2020)

• Record Type: Journal Article
• Authors: Bulik, Cynthia; Kennedy, Martin; Wade, Tracey
• Editors: Evans, David; Medland, Sarah; Gillespie, Nathan
• Is Part Of: Twin research and human genetics. Volume 23:Number 2(2020)
• Page Start: 135
• Page End: 136
• Publication Date: 2020-04
• Subjects: Anorexia nervosa, -- genetic variants, -- eating disorders; Twins -- Periodicals; Multiple birth -- Periodicals; 618.25
• DOI: 10.1017/thg.2020.24
• Languages: English
• ISSNs: 1832-4274

Abstract

Abstract: Identification of genetic variants associated with eating disorders is underway. The Anorexia Nervosa Genetics Initiative, an initiative of the Klarman Family Foundation, has contributed to advancing the field, yielding a large-scale genome-wide association study published in Nature Genetics . Eight genetic variants significantly associated with anorexia nervosa were identified, along with patterns of genetic correlations that suggest both psychiatric and metabolic origins of this serious and life-threatening illness. This article details the role of Professor Nick Martin in contributing to this important collaboration.