Epidemiological and clinical characteristics of a familial cluster of COVID-19. (2020)

• Record Type: Journal Article
• Authors: Sun, Yong; Tian, Lin; Du, Xiaomei; Wang, Hua; Li, Yueshan; Wu, Rangbing
• Is Part Of: Epidemiology and infection. Volume 148(2020)
• Publication Date: 2020
• Subjects: Asymptomatic transmission, -- coronavirus disease 2019, -- Outside Wuhan, -- transmission and clinical characteristics; Communicable diseases -- Periodicals; Epidemiology -- Periodicals; 614.4
• DOI: 10.1017/S0950268820001521
• Languages: English
• ISSNs: 0950-2688

Abstract

Abstract: We report a family cluster of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection involving five patients in a family cluster in Dazhou, China, including the epidemiological, clinical, laboratory and radiological findings. Three-generation transmission was observed. Through epidemiological investigation, we observed asymptomatic transmission to a cohabiting family member, as well as person-to-person transmission of SARS-CoV-2 outside Wuhan city. The asymptomatic transmission demonstrated here provides evidence that there could be a greater risk of Coronavirus Disease 2019 (COVID-19) spread. This cluster also demonstrated that COVID-19 is transmissible during the incubation period of an asymptomatic person. Early isolation and treatment, stressing prevention of cluster outbreaks, could help prevent further spread of the epidemic.