A case of sporotrichosis infection mimicking pyoderma gangrenosum and the role of tissue culture in diagnosis: A case report. (May 2020)

• Record Type: Journal Article
• Authors: Tai, Felicia; Jakubovic, Henry; Alabdulrazzaq, Shaikhah; Alavi, Afsaneh
• Is Part Of: SAGE open medical case reports. Volume 8(2020)
• Publication Date: 2020-05
• Subjects: Pyoderma gangrenosum -- sporotrichosis infection -- sporotrichosis schenckii -- pyoderma gangrenosum diagnostic criteria -- cutaneous sporotrichosis -- ulcer -- deep fungal infection -- histoplasmosis mimic; Clinical medicine -- Case studies -- Periodicals; 616.09
• DOI: 10.1177/2050313X20919600
• Languages: English
• ISSNs: 2050-313X

Abstract

Sporotrichosis infections may cause cutaneous lesions mimicking other infectious or non-infectious causes such as pyoderma gangrenosum. We present a case of cutaneous sporotrichosis misdiagnosed as pyoderma gangrenosum and treated with immunosuppressants for 17 months leading to exacerbation and atypical morphology mimicking Histoplasma organisms on biopsy. Exclusion of infection prior to diagnosing pyoderma gangrenosum is important to prevent iatrogenic immunosuppression, demonstrating the challenges with application of the updated pyoderma gangrenosum diagnostic criteria.