Nano-functionalized long-period fiber grating probe for disease-specific protein detection. Issue 3 (5th January 2018)

• Record Type: Journal Article
• Authors: Tyagi, Deependra; Mishra, Satyendra Kumar; Zou, Bing; Lin, Congcong; Hao, Ting; Zhang, Ge; Lu, Aiping; Chiang, Kin Seng; Yang, Zhijun
• Is Part Of: Journal of materials chemistry. Volume 6:Issue 3(2017)
• Page Start: 386
• Page End: 392
• Publication Date: 2018-01-05
• Subjects: Materials -- Periodicals; Chemistry, Analytic -- Periodicals; Biomedical materials -- Research -- Periodicals; 543.0284
• DOI: 10.1039/c7tb02406a
• Languages: English
• ISSNs: 2050-750X

Abstract

Abstract : Label-free nano-functionalized LPFG based real-time, reusable sensor for sensitive detection of disease-specific proteins. Abstract : Optical biosensors have great significance for rapid and sensitive detection and monitoring of biomolecular interactions. Here, recent advancement in the nano-functionalized long-period fiber grating (LPFG) is used to develop a cost-effective approach for label-free and real-time detection of the carbonic anhydrase-IX (CA9) monoclonal antibody, a diagnostic biomarker in hypoxia condition cultured carcinoma cells.