Chemoresponsive polymer systems for selective molecular recognition of organic molecules in biological systems. (15th October 2020)

• Record Type: Journal Article
• Authors: Gosecka, Monika; Gosecki, Mateusz
• Is Part Of: Acta biomaterialia. Volume 116(2020)
• Page Start: 32
• Page End: 66
• Publication Date: 2020-10-15
• Subjects: Chemoresponsiveness -- Molecular recognition -- Polymer micelle -- Polymerosome -- Hydrogel -- Organogel -- Drug-delivery systems -- Glucose-responsive -- Resorcinol-responsive -- Dopamine-responsive -- Glutathione-responsive; ALL acute lymphoblastic leukemia -- GRIDS glucose-responsive insulin delivery systems -- EDC N-(3- dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride -- NHS N-hydroxysuccinimide -- APBA 3-acrylamidephenylboronic acid -- PBS phosphate buffer saline -- MV methylviologen -- DBF dibenzofuran -- CB[8] cucurbit[8]uril -- LCST lower critical solution temperature -- PNIPAM poly)N-isopropylacrylamide -- CA catechol -- DTT dithiothreitol -- PTX paclitaxel -- DOX doxorubicin -- 6-MP 6-mercaptopurine -- Ara-C Cytarabine -- IgG Immunoglobulin G -- BSA bovine serum albumin -- PEG poly(ethylene glycol) -- PGD polyglycerol dendrimer -- GC glycol chitosan -- PTA cis-3-(9H-Purin-6-ylthio) acrylic acid -- ROS reactive oxygen species -- HSF hydrophilic silk fibroin -- ATP adenosine triphosphate -- Trp trypsin -- BAPNA N-α-benzoyl-DL-arginine-4-nitroanilide -- AIE aggregation-induced emission -- SCS sulfur-carbon-sulfur -- TPE tetraphenylethylene -- TBABr tetrabutylammonium bromide -- DPPST diphenylphosphino)styrene -- RhPN covalently cross-linked rhodamine-phosphine coordination polymer network -- n-BA-n butylacrylate -- DPPST 4-(diphenylphosphino)styrene -- PPGDMA propylene glycol dimethacrylate -- ATRP atom transfer radical polymerization -- RAFT reversible addition-fragmentation chain transfer polymerization -- SPCE screen printed carbon electrode -- Ac-TP acryloyl-3, 5-bis(trifluoromethyl)phenylthiourea -- Ac-β-MAP acryloyl-N-β-L-aspartyl-L-phenylalanine dimethyl ester; Biomedical materials -- Periodicals; 610.28
• DOI: 10.1016/j.actbio.2020.08.039
• Languages: English
• ISSNs: 1742-7061

Abstract

Abstract: Smart polymer materials that respond to a chemical stimulus are applied for the construction of biomedical devices and purification/separation systems. Small organic molecules are a particular type of stimulus. Their abnormal concentration indisputably indicates certain diseases. They are also hazardous environment contaminants. Polymer materials, which structure is selectively changed in the presence of a defined organic compound are promising in view of regulation of certain biomedical functions, as well as in view of chemical detectors construction. This review summarizes the state of the art in the self-assemblies of amphiphilic copolymers and polymer networks sensitive toward organic species, with an emphasis on the reports from the last decade. We focus on the relationship between the selectivity of introduced receptor moieties responsible for the change of material structure, the overall structure of material and its functionality. Graphical abstract: Image, graphical abstract