Risk assessment of bioaccessible trace elements in smoke haze aerosols versus urban aerosols using simulated lung fluids. (January 2016)

• Record Type: Journal Article
• Authors: Huang, Xian; Betha, Raghu; Tan, Li Yun; Balasubramanian, Rajasekhar
• Is Part Of: Atmospheric environment. Volume 125:Part B(2016)
• Page Start: 505
• Page End: 511
• Publication Date: 2016-01
• Subjects: Metal bioaccessibility -- Simulated lung fluids -- Smoke haze -- Health risk assessment -- Aerosols; Air -- Pollution -- Periodicals; Air -- Pollution -- Meteorological aspects -- Periodicals; 551.51
• DOI: 10.1016/j.atmosenv.2015.06.034
• Languages: English
• ISSNs: 1352-2310

Abstract

Abstract: Smoke-haze episodes, caused by uncontrolled peat and forest fires, occur almost every year in the South-East Asian region with increased concentrations of PM2.5 (airborne particulate matter (PM) with diameter ≤ 2.5 μm). Particulate-bound trace elements (TrElems), especially carcinogenic and toxic elements, were measured during smoke haze as well as non-haze periods in 2014 as they are considered to be indicators of potential health effects. The bioaccessibilities of 13 TrElems were investigated using two types of simulated lung fluids (SLFs), Gamble's solution and artificial lysosomal fluid (ALF), instead of the commonly used leaching agent (water). The dissolution kinetics was also examined for these TrElems. Many TrElems showed higher solubility in SLFs, and were more soluble in ALF compared to the Gamble's solution. Cu, Mn and Cd were observed to be the most soluble trace elements in ALF, while in Gamble's solution the most soluble trace elements were Cu, Mn and Zn. The dissolution rates were highly variable among the elements. Health risk assessment was conducted based on the measured concentrations of TrElems and their corresponding toxicities for three possible scenarios involving interactions between carcinogenic and toxic TrElems and SLFs, using the United States Environmental Protection Agency (USEPA) human health risk assessment model. The cumulative cancer risks exceeded the acceptable level (1 in a million i.e. 1 × 10 −6 ). However, the estimation of health quotient (HQ) indicated no significant chronic toxic health effects. The risk assessment results revealed that the assessment of bioaccessibility of particulate-bound TrElems using water as the leaching agent may underestimate the health risk. Highlights: Bioaccessbility of particulate-bound trace elements using simulated lung fluids. Dissolution kinetics of 13 trace elements in simulated lung fluids. Evaluation of bioaccessibility of 13 elements in both haze and non-haze samples. Health Risk assessment for three possible scenarios upon inhalation of PM2.5 . Underestimation of health risk assessment while using water as a leaching agent.