Self‐Assembly of Wireframe DNA Nanostructures from Junction Motifs. (24th July 2019)

• Record Type: Journal Article
• Authors: Huang, Kai; Yang, Donglei; Tan, Zhenyu; Chen, Silian; Xiang, Ye; Mi, Yongli; Mao, Chengde; Wei, Bryan
• Is Part Of: Angewandte Chemie. Volume 131:Number 35(2019)
• Page Start: 12251
• Page End: 12255
• Publication Date: 2019-07-24
• Subjects: DNA-Nanostrukturen -- Drahtgitterstrukturen -- Selbstorganisation -- Verzweigungsmotive; Chemistry -- Periodicals; 540
• DOI: 10.1002/ange.201906408
• Languages: English
• ISSNs: 0044-8249

Abstract

Abstract: Wireframe frameworks have been investigated for the construction of complex nanostructures from a scaffolded DNA origami approach; however, a similar framework is yet to be fully explored in a scaffold‐free "LEGO" approach. Herein, we describe a general design scheme to construct wireframe DNA nanostructures entirely from short synthetic strands. A typical edge of the resulting structures in this study is composed of two parallel duplexes with crossovers on both ends, and three, four, or five edges radiate out from a certain vertex. By using such a self‐assembly scheme, we produced planar lattices and polyhedral objects. Abstract : Verzweigte Angelegenheit : DNA‐Verzweigungsmotive mit Anordnungen in bestimmten Winkeln wurden entwickelt. Mit ihnen wurden zweidimensionale Drahtgitterstrukturen und dreidimensionale Polyeder konstruiert.