Nickel‐Catalyzed Arylboration of Alkenylarenes: Synthesis of Boron‐Substituted Quaternary Carbons and Regiodivergent Reactions. Issue 32 (28th June 2019)

• Record Type: Journal Article
• Authors: Chen, Liang‐An; Lear, Alan R.; Gao, Pin; Brown, M. Kevin
• Is Part Of: Angewandte Chemie international edition. Volume 58:Issue 32(2019)
• Page Start: 10956
• Page End: 10960
• Publication Date: 2019-06-28
• Subjects: alkenes -- arylboration -- boron -- cross coupling -- nickel; Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201904861
• Languages: English
• ISSNs: 1433-7851

Abstract

Abstract: A method for the construction of boron‐substituted quaternary carbons or diarylquaternary carbons by arylboration of highly substituted alkenylarenes is presented. A wide range of alkenes and arylbromides can participate in this reaction thus allowing for a diverse assortment of products to be prepared. In addition, a solvent dependent regiodivergent arylboration of 1, 2‐disubstituted alkenylarenes is presented, thus greatly increasing the scope of products that can be accessed. Abstract : Boron‐substituted quaternary carbon or diarylquaternary carbon centers are constructed by arylboration of highly substituted alkenylarenes. A wide range of alkenes and arylbromides can participate in this reaction. In addition, a solvent dependent regiodivergent arylboration of 1, 2‐disubstituted alkenylarenes is presented, thus greatly increasing the scope of products that can be accessed.