Substrate‐Selective Catalysis. Issue 42 (3rd October 2014)

• Record Type: Journal Article
• Authors: Lindbäck, Emil; Dawaigher, Sami; Wärnmark, Kenneth
• Is Part Of: Chemistry. Volume 20:Issue 42(2014)
• Page Start: 13432
• Page End: 13481
• Publication Date: 2014-10-03
• Subjects: competitive experiments -- heterogeneous catalysis -- homogeneous catalysis -- receptors -- substrate selectivity; Chemistry -- Periodicals; 540
• DOI: 10.1002/chem.201402548
• Languages: English
• ISSNs: 0947-6539

Abstract

Abstract: Substrate selectivity is an important output function for the validation of different enzyme models, catalytic cavity compounds, and reaction mechanisms as demonstrated in this review. In contrast to stereo‐, regio‐, and chemoselective catalysis, the field of substrate‐selective catalysis is under‐researched and has to date generated only a few, but important, industrial applications. This review points out the broad spectrum of different reaction types that have been investigated in substrate‐selective catalysis. The present review is the first one covering substrate‐selective catalysis and deals with reactions in which the substrates involved have the same reacting functionality and the catalysts is used in catalytic or in stoichiometric amounts. The review covers real substrate‐selective catalysis, thus only including cases in which substrate‐selective catalysis has been observed in competition between substrates. Abstract : Catalyzing the right stuff : This review treats the concept of substrate‐selective catalysis, covering the developments in the field to date. Examples of substrate‐selective catalysis have been found in major chemical reactions: oxidation, reduction, hydroformylation, addition, condensation, substitution, CC coupling, and transamination. The review covers the progress from both the research laboratory and industry in the area using both homo‐ and heterogeneous catalysts.