Novel case of recurrent intraventricular atypical central neurocytoma with prominent gangliogliomatous differentiation in a 10‐year‐old boy with 10 years of follow up. Issue 5 (24th July 2018)

• Record Type: Journal Article
• Authors: Tan, Char‐Loo; Landi, Daniel; Fuchs, Herbert; McLendon, Roger E.
• Is Part Of: Neuropathology. Volume 38:Issue 5(2018)
• Page Start: 542
• Page End: 548
• Publication Date: 2018-07-24
• Subjects: central neurocytoma -- ganglioglioma -- ganglion cells -- intraventricular -- neuron; Nervous system -- Diseases -- Periodicals; Nervous system -- Pathophysiology -- Periodicals; 616.8047
• DOI: 10.1111/neup.12502
• Languages: English
• ISSNs: 0919-6544

Abstract

Abstract : Central neurocytoma is a rare neuronal tumor that typically occurs in young adults. Infrequently, these tumors exhibit advanced neuronal maturation and glial differentiation, giving rise to a histologically diverse tumor, in contrast to a typical central neurocytoma. We present a novel case of intraventricular central neurocytoma with prominent gangliogliomatous differentiation that developed atypical features upon recurrence after 10 years of follow up in a 10‐year‐old boy. Our case provides insight into the divergent differentiation capability of a neurocytic tumor and illustrates the diverse histological features of this rare entity.