The direct C3 chalcogenylation of indolines using a graphene-oxide-promoted and visible-light-induced synergistic effect. (1st October 2020)

• Record Type: Journal Article
• Authors: Liu, Chunping; Peng, Xiangjun; Hu, Dan; Shi, Feng; Huang, Panpan; Luo, Juanjuan; Liu, Qian; Liu, Liangxian
• Is Part Of: New journal of chemistry. Volume 44:Number 40(2020)
• Page Start: 17245
• Page End: 17251
• Publication Date: 2020-10-01
• Subjects: Chemistry -- Periodicals; Chimie -- Périodiques; 540
• DOI: 10.1039/d0nj00747a
• Languages: English
• ISSNs: 1144-0546

Abstract

Abstract : A green methodology for the construction of carbon–chalcogen (S and Se) bonds via a GO-promoted and metal-free light-induced synergistic effect is demonstrated. Abstract : A new and efficient method for the C3–chalcogenylation of indolines, employing visible light irradiation, and graphene oxide as a promoter, at room temperature has been achieved. The features of the reaction include the use of metal-free and iodine-free conditions, simple operation, high yields, the use of a non-toxic and easy-to-handle oxidant, and gram-scalable synthesis. This benign protocol allows access to a wide range of 3-arylthioindoles, 3-arylselenylindoles, and even 3-thiocyanatoindoles in good to excellent yields.