68Ga–Prostate-Specific Membrane Antigen PET–Positive Paget Bone Disease With Metastatic Prostatic Carcinoma. (September 2020)

• Record Type: Journal Article
• Authors: Engur, Ceren Ozge; Turoglu, Halil Turgut; Ozguven, Salih; Tanidir, Yiloren; Erdil, Tanju Yusuf
• Is Part Of: Clinical nuclear medicine. Volume 45:Number 9(2020)
• Publication Date: 2020-09
• Subjects: Paget disease of bone -- 99mTc-methylene diphosphonate bone scintigraphy -- prostate cancer -- bone metastases -- SPECT-CT (single photon emission computerized tomography/computed tomography) -- 68Ga-PSMA PET-CT; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000003198
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: Paget bone disease is a chronic benign bone disease characterized by excessive and abnormal bone remodeling. The scintigraphic and bone SPECT/CT hybrid imaging appearances of the affected bone(s) depend on the stage of the disease. We report the case of a patient newly diagnosed with prostate cancer who was found to have multiple osseous metastases, with coexisting Paget disease in the left hemipelvis diagnosed because of typical scintigraphic and SPECT/CT appearance. 68 Ga–prostate-specific membrane antigen PET/CT was also performed for initial staging. Pagetoid bones showed increased prostate-specific membrane antigen uptake like skeletal metastases.