Typical Acute Traumatic Fracture Healing in an 83-Year-Old Man Undergoing 223Ra Treatment for Prostatic Cancer Bone Metastases. (September 2020)

• Record Type: Journal Article
• Authors: Minekawa, Thaís; Lima, Mariana; Moraes, André; Santos, Allan; Etchebehere, Elba
• Is Part Of: Clinical nuclear medicine. Volume 45:Number 9(2020)
• Publication Date: 2020-09
• Subjects: 223Ra -- elderly -- fracture consolidation -- prostate cancer; Nuclear medicine -- Periodicals; Radioisotope scanning -- Periodicals; Nuclear Medicine -- Periodicals; 616.07575
• DOI: 10.1097/RLU.0000000000003173
• Languages: English
• ISSNs: 0363-9762

Abstract

Abstract : Abstract: We report the case of a fracture healing after 223 Ra in an 83-year-old wheelchair-bound man with prostate castration-resistant adenocarcinoma treated due to uncontrollable pain from widespread bone metastases. The patient fractured both right tibia and fibula 15 days prior to the first 223 Ra cycle. After the first cycle, there was complete remission of his metastatic bone pain; after the second cycle, he began walking with support, which helped improve fracture healing; and after the third cycle, he presented complete mobility. Posttreatment images showed consolidated fractures. By improving metastatic bone pain with 223 Ra, consolidation of the insufficiency fracture was possible.